Neuroscience rarely enjoys clean experiments. Most brain disorders are mosaics of risk genes, aging, lifestyle and chance that leave their origins obscured. Huntington's disease (HD) is different. It ...

The genetic mutation that causes Huntington’s disease (HD) – a devastating brain disease that disrupts mobility and diminishes cognitive ability – may also enhance early brain development and play a ...

Usually, most of us can zip a zipper without incident. But sometimes, an unwary dresser makes an alignment error that goes undetected until the ends of a garment don ...

Huntington’s Disease organoids (right) exhibit almost no neural progenitors (red) and also show defects in cellular polarity (yelllow). These defects have been described in the literature in human ...