In a recent article published in Nature Medicine, researchers investigated the potential implications of single-nucleotide variations in gut-residing bacterial species (microbiome) on human health.
CMD-related SNPs. CMD, coronary microvascular dysfunction; SNP, single nucleotide polymorphism. The findings suggest that a genetics-driven approach could revolutionize CMD diagnosis and treatment, ...
Pharmacogenetic factors predicting the need for a higher dose of imatinib. Results: 29 SNPs were detected in the case-cohort population, 8 of which were analyzed in all 568 pts. IVS14+1G>A, 2846A>T, ...
Analysis of primary and acquired resistance to cetuximab from multiomic data in the New EPOC trial. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include ...
The promise of pharmacogenetics will not be realized easily. To date, most studies have focused on individual SNPs (single nucleotide polymorphisms), or perhaps a few, but none have considered the ...
Association studies that correlate SNP patterns to disease risks are straightforward. Clues to the past can be subtler, but they are found at all levels of evolution--from the great branching points ...
About 50% of patients with lung cancer present with metastatic disease; researchers have shown that breast cancer metastasis-suppressor 1 (BRMS1) suppresses metastases in non-small-cell lung cancer ...
Researchers from Tokyo Medical and Dental University (TMDU) and the Universities of Helsinki and Barcelona have identified a single nucleotide change key in the evolution of human skull morphology, ...
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